CHLORHEXIDINE GLUCONATE

PRODUCT IDENTIFICATION
CAS NO

18472-51-0

CHLORHEXIDINE 

EINECS NO. 242-354-0
FORMULA

C22H30Cl2N10·2C6H12O7

MOL WT. 897.77

HS CODE

  

TOXICITY

 Oral rat LD50:2 gm/kg
SYNONYMS

Peridex®; Periochip®, Periogard Oral Rinse®;

1,1'-Hexam ethylene bis(5- (p-chlorophenyl) biguanide) digluconate; 1,6-Bis(5-(p- chlorophenyl) biguandino)hexane digluconate; Arlacide G; Bacticlens; Hibitane 5; Orahexal; Peridex; D-Gluconsäure, N,N''-Bis (4-chlorphenyl) -3,12-diimino-2,4,11,13- tetraazatetradecan diamidin (German); ácido D-glucónico, N,N''-bis (4-clorofenil)- 3,12-diimino-2,4,11,13- tetraazatetradecanodiamidina (Spanish), Acide D-gluconique, N,N''-bis(4-chlorophényl)- 3,12-diimino-2,4,11,13- tétraazatétradécanediamidine (French); D-Gluconic acid, N,N''-bis(4-chlorophenyl)-3,12- diimino-2,4,11,13- tetraaza tetradecanediimidamide (2:1);

SMILES

 

CLASSIFICATION

DISINFECTANTS /

PHYSICAL AND CHEMICAL PROPERTIES
PHYSICAL STATE colorless to pale yellow color
MELTING POINT 134 C
BOILING POINT

 

SPECIFIC GRAVITY

1.06

SOLUBILITY Miscible with water, soluble in ethanol & acetone
pH  
VAPOR DENSITY

 

FLASH POINT

 

APPLICATIONS
Chlorhexidine is an antiseptic effective against a wide variety of gram-negative and gram-positive organisms, facultative anaerobes, aerobes, and yeast. Chlorhexidine is used as an ingredient of bacteriostatic and bacteriocidal by the activity of membrane disruption in a general purpose skin general skin cleansers, surgical scrub, germicidal hand rinses and animal disinfection products. It is used as a topical antiinfective for mucous membranes and as a preservative for eye drops. Chlorhexidine is also used as an antiseptic ingredient used in mouthwash to prevent oral plaque, oral bacteria and in treating gingivitis. Its salts for commercial uses include:
Chlorhexidine salt

CAS RN
Chlorhexidine diacetate 56-95-1
Chlorhexidine dihydrochloride 3697-42-5
Chlorhexidine digluconate 18472-51-0
Chlorhexidine phosphanilate 77146-42-0

In addition to antibacterial activity, chlorhexidine phosphanilate is also used as a spermatocidal agent.

Active ingredients in mouthwash or dental caries prophylactic include;

Ingredient

CAS RN
Amosan 8059-88-9
Benzalkonium chloride 8001-54-5
Cetylpyridinium chloride 123-03-5
Chlorhexidine gluconate 18472-51-0
Chlorhexidine55-56-1
Dectaflur 36505-83-6
Eucalyptol 470-82-6
Hetaflur 3151-59-5
Hydrogen peroxide 7722-84-1
Ipexidine mesylate 69017-90-9
Listerine 51273-66-6
Meridol 120812-75-1
Metesculetol 52814-39-8
Methyl salicylate 119-36-8
Olaflur 6818-37-7
Rhatany 84775-95-1
Salifluor 78417-90-0
Sanguinarine 2447-54-3
Sodium monofluorophosphate 10163-15-2
Sodium fluoride 7681-49-4
Stannous fluoride 7783-47-3
Thymol 89-83-8
Tiodonium chloride 38070-41-6
Zinc chloride 7646-85-7
Zinc fluoride 7783-49-5
SALES SPECIFICATION

BIBLIOGRAPHY

USP / BP
APPEARANCE

Colorless to Pale Yellow Clear Liquid

CONTENT

 19.0 - 21.0 % (Chlorhexidine Gluconate)

pH (5% SOL.)

 5.5 - 7.0
MELTING POINT 132 - 136 C
P-CHLOROANILINE 500ppm max

RESIDUE ON IGNITION

0.1% max
SPECIFIC GRAVITY

1.06 - 1.07
TRANSPORTATION
PACKING

 

HAZARD CLASS  
UN NO.  
ADDITIONAL CAS RN
12068-31-4; 14007-07-9; 21293-24-3; 23289-58-9; 40330-16-3; 51365-13-0; 52196-45-9; 52387-19-6; 60042-57-1; 60404-86-6; 82432-16-4; 105791-72-8; 124973-71-3; 150621-85-5; 151498-43-0
PRICE

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